TRICHLOROETHYLENE
MSDS Number: T4940 --- Effective Date: 09/14/00
1. Product Identification
Synonyms: Trichloroethene; TCE; acetylene trichloride;
Ethinyl trichloride
CAS No.: 79-01-6
Molecular Weight:
131.39
Chemical Formula: C2HCl3
Product Codes:
J.T.
Baker: 5376, 9454, 9458, 9464, 9473, 9474
Mallinckrodt: 8598, 8600, 8633
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Trichloroethylene 79-01-6 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
WARNING! HARMFUL IF SWALLOWED OR INHALED. AFFECTS HEART, CENTRAL
NERVOUS SYSTEM, LIVER AND KIDNEYS. CAUSES SEVERE SKIN IRRITATION. CAUSES
IRRITATION TO EYES AND RESPIRATORY TRACT. SUSPECT CANCER HAZARD. MAY CAUSE
CANCER. Risk of cancer depends on level and duration of exposure.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for
your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 3 - Severe (Cancer Causing)
Flammability Rating: 1 -
Slight
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT
HOOD; PROPER GLOVES
Storage Color Code: Blue (Health)
-----------------------------------------------------------------------------------------------------------
Potential Health Effects
----------------------------------
Inhalation:
Vapors can irritate the respiratory tract.
Causes depression of the central nervous system with symptoms of visual
disturbances and mental confusion, incoordination, headache, nausea, euphoria,
and dizziness. Inhalation of high concentrations could cause unconsciousness,
heart effects, liver effects, kidney effects, and death.
Ingestion:
Cases irritation to gastrointestinal tract. May also cause effects similar
to inhalation. May cause coughing, abdominal pain, diarrhea, dizziness,
pulmonary edema, unconsciousness. Kidney failure can result in severe cases.
Estimated fatal dose is 3-5 ml/kg.
Skin Contact:
Cause
irritation, redness and pain. Can cause blistering. Continued skin contact has
a defatting action and can produce rough, dry, red skin resulting in secondary
infection.
Eye Contact:
Vapors may cause severe irritation with
redness and pain. Splashes may cause eye damage.
Chronic Exposure:
Chronic exposures may cause liver, kidney, central nervous system, and
peripheral nervous system effects. Workers chronically exposed may exhibit
central nervous system depression, intolerance to alcohol, and increased
cardiac output. This material is linked to mutagenic effects in humans. This
material is also a suspect carcinogen.
Aggravation of Pre-existing
Conditions:
Persons with pre-existing skin disorders, cardiovascular
disorders, impaired liver or kidney or respiratory function, or central or
peripheral nervous system disorders may be more susceptible to the effects of
the substance.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. Call a
physician.
Ingestion:
Induce vomiting immediately as directed
by medical personnel. Never give anything by mouth to an unconscious person.
Call a physician.
Skin Contact:
Immediately flush skin with
plenty of soap and water for at least 15 minutes while removing contaminated
clothing and shoes. Get medical attention. Wash clothing before reuse.
Thoroughly clean shoes before reuse.
Eye Contact:
Immediately
flush eyes with plenty of water for at least 15 minutes, lifting lower and
upper eyelids occasionally. Get medical attention immediately.
Note
to Physician:
Do not administer adrenaline or epinephrine to a victim
of chlorinated solvent poisoning.
5. Fire Fighting Measures
Fire:
Autoignition temperature: 420C
(788F)
Flammable limits in air % by volume:
lel: 8; uel: 12.5
Explosion:
A strong ignition source, e. g., a welding torch,
can produce ignition. Sealed containers may rupture when heated.
Fire
Extinguishing Media:
Use water spray to keep fire exposed containers
cool. If substance does ignite, use CO2, dry chemical or foam.
Special
Information:
In the event of a fire, wear full protective clothing and
NIOSH-approved self-contained breathing apparatus with full facepiece operated
in the pressure demand or other positive pressure mode. Combustion by-products
include phosgene and hydrogen chloride gases. Structural firefighters'
clothing provides only limited protection to the combustion products of this
material.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition.
Wear appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from entering.
Contain and recover liquid when possible. Use non-sparking tools and
equipment. Collect liquid in an appropriate container or absorb with an inert
material (e. g., vermiculite, dry sand, earth), and place in a chemical waste
container. Do not use combustible materials, such as saw dust. Do not flush to
sewer! US Regulations (CERCLA) require reporting spills and releases to soil,
water and air in excess of reportable quantities. The toll free number for the
US Coast Guard National Response Center is (800) 424-8802.
7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry,
ventilated area. Protect against physical damage. Isolate from any source of
heat or ignition. Isolate from incompatible substances. Containers of this
material may be hazardous when empty since they retain product residues
(vapors, liquid); observe all warnings and precautions listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
Trichloroethylene:
-OSHA
Permissible Exposure Limit (PEL):
100 ppm (TWA), 200 ppm (Ceiling),
300
ppm/5min/2hr (Max)
-ACGIH Threshold Limit Value (TLV):
50 ppm (TWA)
100 ppm (STEL);
listed as A5, not suspected as a human carcinogen.
Ventilation System:
A system of local and/or general exhaust is
recommended to keep employee exposures below the Airborne Exposure Limits.
Local exhaust ventilation is generally preferred because it can control the
emissions of the contaminant at its source, preventing dispersion of it into
the general work area. Please refer to the ACGIH document, Industrial
Ventilation, A Manual of Recommended Practices, most recent edition, for
details.
Personal Respirators (NIOSH Approved):
If the exposure
limit is exceeded and engineering controls are not feasible, wear a supplied
air, full-facepiece respirator, airlined hood, or full-facepiece
self-contained breathing apparatus. Breathing air quality must meet the
requirements of the OSHA respiratory protection standard (29CFR1910.134). This
substance has poor warning properties. Where respirators are required, you
must have a written program covering the basic requirements in the OSHA
respirator standard. These include training, fit testing, medical approval,
cleaning, maintenance, cartridge change schedules, etc. See 29CFR1910.134 for
details.
Skin Protection:
Wear impervious protective clothing,
including boots, gloves, lab coat, apron or coveralls, as appropriate, to
prevent skin contact. Neoprene is a recommended material for personal
protective equipment.
Eye Protection:
Use chemical safety
goggles and/or a full face shield where splashing is possible. Maintain eye
wash fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Clear, colorless liquid.
Odor:
Chloroform-like odor.
Solubility:
Practically insoluble in
water. Readily miscible in organic solvents.
Specific Gravity:
1.47 @ 20C/4C
pH:
No information found.
% Volatiles
by volume @ 21C (70F):
100
Boiling Point:
87C (189F)
Melting Point:
-73C (-99F)
Vapor Density (Air=1):
4.5
Vapor Pressure (mm Hg):
57.8 @ 20C (68F)
Evaporation Rate (BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and
storage. Will slowly decompose to hydrochloric acid when exposed to light and
moisture.
Hazardous Decomposition Products:
May produce carbon
monoxide, carbon dioxide, hydrogen chloride and phosgene when heated to
decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong caustics and alkalis, strong
oxidizers, chemically active metals, such as barium, lithium, sodium,
magnesium, titanium and beryllium, liquid oxygen.
Conditions to
Avoid:
Heat, flame, ignition sources, light, moisture, incompatibles
11. Toxicological Information
Toxicological Data:
Trichloroethylene: Oral rat LD50:
5650 mg/kg; investigated as a tumorigen, mutagen, reproductive effector.
Reproductive Toxicity:
This material has been linked to
mutagenic effects in humans.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Trichloroethylene (79-01-6) No Yes 2A
12. Ecological Information
Environmental Fate:
When released into the soil, this
material may leach into groundwater. When released into the soil, this
material is expected to quickly evaporate. When released to water, this
material is expected to quickly evaporate. This material has an
experimentally-determined bioconcentration factor (BCF) of less than 100. This
material is not expected to significantly bioaccumulate. When released into
the air, this material may be moderately degraded by reaction with
photochemically produced hydroxyl radicals. When released into the air, this
material is expected to have a half-life between 1 and 10 days.
Environmental Toxicity:
The LC50/96-hour values for fish are
between 10 and 100 mg/l. This material is expected to be slightly toxic to
aquatic life.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be
handled as hazardous waste and sent to a RCRA approved incinerator or disposed
in a RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local disposal
regulations may differ from federal disposal regulations. Dispose of container
and unused contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: TRICHLOROETHYLENE
Hazard Class:
6.1
UN/NA: UN1710
Packing Group: III
Information
reported for product/size: 5GL
International (Water,
I.M.O.)
-----------------------------
Proper Shipping Name:
TRICHLOROETHYLENE
Hazard Class: 6.1
UN/NA: UN1710
Packing Group: III
Information reported for product/size: 5GL
International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: TRICHLOROETHYLENE
Hazard Class:
6.1
UN/NA: UN1710
Packing Group: III
Information
reported for product/size: 5GL
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Trichloroethylene (79-01-6) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Trichloroethylene (79-01-6) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Trichloroethylene (79-01-6) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Trichloroethylene (79-01-6) 100 U228 No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No
Reactivity: No (Pure / Liquid)
WARNING:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO
THE STATE OF CALIFORNIA TO CAUSE CANCER.
Australian Hazchem
Code: No information found.
Poison Schedule: S6
WHMIS:
This MSDS has been prepared according to the hazard
criteria of the Controlled Products Regulations (CPR) and the MSDS contains
all of the information required by the CPR.
16. Other Information
NFPA Ratings: Health: 2 Flammability: 1
Reactivity: 0
Label Hazard Warning:
WARNING! HARMFUL IF
SWALLOWED OR INHALED. AFFECTS HEART, CENTRAL NERVOUS SYSTEM, LIVER AND
KIDNEYS. CAUSES SEVERE SKIN IRRITATION. CAUSES IRRITATION TO EYES AND
RESPIRATORY TRACT. SUSPECT CANCER HAZARD. MAY CAUSE CANCER. Risk of cancer
depends on level and duration of exposure.
Label Precautions:
Do not get in eyes, on skin, or on clothing.
Do not breathe
vapor.
Keep container closed.
Use only with adequate
ventilation.
Wash thoroughly after handling.
Keep away from heat and
flame.
Label First Aid:
If swallowed, induce vomiting
immediately as directed by medical personnel. Never give anything by mouth to
an unconscious person. If inhaled, remove to fresh air. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. In case of
contact, immediately flush eyes or skin with plenty of water for at least 15
minutes. Remove contaminated clothing and shoes. Wash clothing before reuse.
In all cases call a physician. Note to physician: Do not administer adrenaline
or epinephrine to a victim of chlorinated solvent poisoning.
Product
Use:
Laboratory Reagent.
Revision Information:
MSDS
Section(s) changed since last revision of document include: 8, 11.
Disclaimer:
************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or
accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this
product. Individuals receiving the information must exercise their independent
judgment in determining its appropriateness for a particular purpose.
MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER
EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE
INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES
RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************
Prepared by: Strategic Services Division
Phone Number: (314)
539-1600 (U.S.A.)